
Principle Project Lead
At Castor, we’re modernizing the backbone of clinical research
Clinical trials are the gatekeepers of human health, yet the industry is still bogged down by fragmented, manual processes that can waste time and exclude patient populations. At Castor, we are building the operating system for the next era of clinical research.
We provide a modular cloud platform designed to run trials end-to-end. Our foundation is a robust Electronic Data Capture (EDC) system, supported by eConsent for recruitment and screening and eCOA to accurately capture patient reported outcomes. We don’t just stop at data collection; we use Castor Catalyst (our high-precision AI automation) to strip away the manual effort that historically makes research slow and expensive.
How we work: Trust over tracking
We are a remote-first company built on the belief that talented people do their best work when they have the agency to manage their own lives. We believe that high performance requires a foundation of trust, health, and cutting-edge support.
Work-life integration: We don't believe in performative presence. We trust you to own your schedule and show up for your team, while also making space for your life outside of work.
Deep work & async: We protect your time. We prioritize thoughtful, asynchronous communication so you can focus on solving hard problems without a calendar full of status update meetings.
Radical candor: We value the truth over hierarchy. We give and receive direct feedback because that’s how we grow—as individuals and as a company.
Your mission and impact
As a Principle Project Lead you will lead our most complex, multi-component, multi-country studies, serving as a subject matter expert. Your value to the business lies in your critical thinking and ability to translate high-level, often vague requirements into robust, technically and operationally sound project architectures.
This is not traditional task-tracking, but high-autonomy and consultative on specialised or new services. You will navigate the increased variables and technical and operational dependencies that come with complex studies, operating with minimal oversight. You will act as the pivotal bridge and consultant to the customer, taking ownership of the end-to-end delivery from ensuring internal project cohesion to leveraging your risk expertise to confidently articulate challenges and guide external stakeholders to the best possible solution.
Who are you
You are energized by first of their kind studies
You naturally shift from simple process following to active solution leading, applying deep critical thinking to every challenge
You remain focused and effective when faced with shifting priorities, rapid change, or undefined project parameters
You act as a high-level consultant to clients, building trust through advocacy and persuasive communication.
You proactively navigate risk, identifying downstream impacts early and architecting solutions that safeguard project integrity.
You are a self-starter who masters the art of remote collaboration. You value deep work and asynchronous communication to drive results
Giving and receiving feedback are necessary to win as a team. You give and receive direct, data-driven feedback, even when it’s uncomfortable
What you’ll bring
Proven expertise in managing highly complex projects within the Software Development Lifecycle (SDLC) for clinical software
Strong understanding of EDC/CDMS, eConsent and eCOA solutions, services and operational strategies
Experience with eCOA services scale licensing, translations, device provisioning, Helpdesk and data management
Strong experience of using project tools such as Jira, Confluence and Microsoft Project (or equivalent)
Deep understanding of the regulatory landscape and industry trends to guide project strategy
Comprehensive knowledge of clinical study operations, ensuring technical solutions align with site workflows, patient centricity, and study-specific operational requirements
Direct experience or foundational understanding of Real-World Evidence (RWE) studies, including the unique data capture and longitudinal tracking needs of late-phase research
Accepting candidates +2/-2 CET. At this time, we cannot accept applications from France, Germany, Spain, Bulgaria, or Switzerland.
How we invest in you
High performance isn't sustainable without real support. We provide the infrastructure you need to stay healthy, focused, and rewarded.
Rest is non-negotiable: Unlimited annual leave with 25-day minimum. We don’t just allow time off; we expect you to take it.
Downtime weeks: Once a quarter, the whole company shifts gears. No new shipping—just a week for deep focus, learning, or catching up so we can start the next quarter fresh.
AI-first culture: We provide the tools and training to ensure you’re spending your energy on high-value work, not manual repetition.
Real ownership: All Castor team members are offered options through our Employee Stock Option Plan (ESOP).
Comprehensive wellbeing: Free access to Open Up for mental health, specialized sleep courses (for you and your family), and a budget to make your home office a place you actually want to be.
Annual bonus: A guaranteed "Happy Holidays" bonus every December.
Belonging at Castor
We build products to make research accessible to everyone, and we believe our team should reflect that same diversity.
Our remote setup is designed to support you as a whole person—your family, your mental health, and your authentic self. We don't care about your background as much as we care about your perspective and your expertise. We strongly encourage applications from women, people of color, and the LGBTQ+ community. Please feel free to share the pronouns you use (for example she/her/hers, he/her/his, they/them/theirs, etc.).
Don't wait, tomorrow could be too late.
About the company
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